Over the course of her career, she saw action against the Klingons, Breen, Tzenkethi, Dominion, and Cardassians.
After a comprehensive refit, she served as a testbed for several new technologies at Utopia Planitia.
Lieutenant Commander Gedna Tachion came aboard as Chief of Security and Second Officer, at Starbase 37. The ship then made a resupply run to the Federation colony on Dorvan V, dropping recently commissioned Ensign Chakotay off on his homeworld. Tachion and the Ensign stayed behind with a shuttle to examine the colony's defense grid while the Ambassador moved on to the next colony.
During the Tzenkethi War, the Ambassador sent a team led by then Lieutenant Commander Gedna Tachion to a planet in order to secure a hospital against an oncoming Tzenkethi armada. Tachion led the team and patients into a bar a few blocks away. They holed up for five days, defending it against enemy ground forces. Their defense tied up Tzenkethi ground forces long enough for the ship to evacuate 496 other civilians from the planet. The evacuees were taken to the nearby Helaspont Station.
- Captain Trefi
- CDR Ronald Garret (2361)
- LCDR Clifford Huxtable (by 2351)
- LCDR Gedna Tachion (2351 - 2357)
- LT Roger Deict (2358 - 2361)