The USS Saipan was a Tarawa class  Planetary Assault Vessel that served in the Sixth Fleet during the Dominion War. The 26th Marine Expeditionary Unit was assigned to her during the war.

She was launched from the Centauri Spaceworks in 2332.

After Operation Return she was assigned to Prophet's Landing to construct headquarters facilities for the Sixth Fleet on the planet. The Saipan offloaded four fighters, a Talon class scout and many prefabricated buildings.