The USS Thomas Paine was a New Orleans class heavy frigate serving in Starfleet during the 24th century.
Rixx assumed command of the vessel prior to attending the Altarian Conference in 2358 and remained in the center until transferring to the USS Beowulf in 2372.
The vessel was part of a joint Starfleet-Vulcan operation to combat Orion Syndicate arms smuggling operations to the Vulcan Isolation Movement in 2365.
The frigate transported a team to Starbase 12 to assess the crew of the USS Bozeman following their reemergence from nine decades in a temporal causality loop.
In 2372 the Thomas Paine was one of six starships suspected of being part of Admiral Leyton's conspiracy. ("Space Jacking Prefix")
By 2375 Stefan Bartok was the vessel's XO.